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That being said, medical cannabis isn’t the same as hemp-derived CBD oil. There are also other difficulties in researching the effects of cannabis. This causes confounding factors, where questions arise as to whether the tobacco, the cannabis, or both that have caused a cancer. Another difficulty researchers have is in recruiting people who smoke cannabis into studies.

• It states that some individuals are, for various reasons, willing to try multiple recreational substances.
• Most adults can benefit from the use of CBD products in some way.
• “Canada becomes second nation in the world to legalize marijuana”.
• Once again, the people who inhaled cannabis said they felt less anxious, though that came at a cost, since they also felt high.

A combination of CBD and THC appears to be hugely effective at reducing pain, muscle spasms and fatigue . One of the most common reasons people use CBD is to help treat various medical can cbd oil help you lose weight conditions and, more specifically, to treat different types of pain from those conditions. Our website services, content and products are for informational purposes only.

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To that end, the brand is also on a mission to make CBD accessible to everyone. In order for FAB CBD to bring its highly-rated, top-shelf products to everyone, the team knew that it had to have the highest and toughest standards in the industry. FAB CBD is also unique in that all of the staff has had experience in does cbd oil help with nausea the health and wellness industries. Therefore, they know what it takes to put forth clean, potent products that benefit their customers’ health and wellness. CBD Clinicals can help you find the best cannabidiol products for your needs. Neuropathic pain also disrupts sleep, as the pain is sometimes worse at night.

It is difficult to determine which dose is best for treating specific health problems. CBD may help people with schizophrenia and other mental health conditions by reducing psychotic symptoms, according to research . Overall, these findings are encouraging, but more research into the potential benefits of CBD treatment on heart health is needed. High blood pressure has been linked to an increased risk of a variety of health problems, including stroke, heart attack, and metabolic syndrome . However, the FDA has approved one CBD product for the treatment of several seizure disorders.

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CBD may possess some anti-anxiety and anti-emetic (anti-vomiting) characteristics, according to a report in the Journal of Psychopharmacology. Meanwhile, a study published in the Journal of Experimental Medicine demonstrated one mechanism by which CBD inhibits inflammatory and neuropathic pain. FDA approves first drug comprised of an active ingredient derived from marijuana to treat rare, severe forms of epilepsy . CBD and THC are two of the most prominent cannabinoids found in the cannabis plant. However, CBD doesn’t cause the euphoric effects that occur with THC. Some people may prefer to use CBD because of the lack of this side effect.

These compounds create a unique synergy known as the entourage effect. This concept was brought up in 1988 and further elaborated on in 2011 by does cbd oil help cll E.B. In the entourage effect, the sum of all active ingredients in the plant is more potent therapeutically than each compound in isolation.

But a new form of medication called CBD has now hit the market, and it’s proving to be even better than regular drugs at killing muscle pain. According to the researchers, 25mg was the how does cbd oil help with seizures most effective anxiety dosage, but higher dosages were required to address disturbed sleep. During the three-month study, investigators followed up with the participants every month.

• These side effects are part of the compound’s psychoactive properties.
• According to one review, Sativex may help people with MS-related neuropathic pain and chronic severe neuropathic pain.
• If a drug’s efficacy depends on its metabolized product, CBD could render it less effective.
• It is one of 113 identified cannabinoids in cannabis plants, along with tetrahydrocannabinol , and accounts for up to 40% of the plant’s extract.
• In 2016, a group of Colorado Natives created CBDistillery as a way to fight against subpar CBD brands that were flooding into the industry.

However, thanks to the 2018 Farm Bill, by law they are required to have 0.3% or less THC. Thankfully, only hemp-derived CBD products are legally allowed, and it just so happens that the hemp plant is bred to contain very low levels of THC. Moreover, you cannot get “high” from any full-spectrum hemp-derived CBD products. The brand also obtains all of its pure and potent extracts through the industry preferred CO2 extraction process. It’s no secret that pain is a major part of many people’s everyday lives. In 2019, the CDC found that over 20 percent of adults live with chronic pain, while over seven percent of adults suffer from high-impact chronic pain.

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On the market today; it was the first FDA-approved CBD epilepsy treatment. On the other hand, some treatments can help alleviate the symptoms, treat pain or slow down the progression of the disease. — they are considered exacerbations and are defined as joint and muscle pain, fever, fatigue, eye inflammation with eye dryness, and a higher risk of blood clotting. The pursuit in trying to find the cure for lupus continues as the therapeutic potential of CBD is yet to be fully discovered. Nevertheless, there is ample evidence today to begin engineering a novelty lupus medication.

CBD Gummies is a clinically proven supplement to assist to improve your health. It contains cannabidiol Gummies that can be consumed without any prescription. It contains essential elements that are able to improve your health, relieve chronic pains as well as providing your body with essential nutrients. Chronic Pain Chronic pain is pain that persists or progresses over a long period of time. In contrast to acute pain that arises suddenly in response to a specific injury and is usually treatable, chronic pain persists over time and is often resistant to medical treatments.

We may not have all the evidence we’d like, but if CBD can safely improve your symptoms, it may be worth considering. CBD should be one part of an overall pain management plan that includes nonmedication options and psychological support. If considering a CBD product, choose one that has been independently tested for purity, potency, and safety — for example, look for one that has received a “Good Manufacturing Practices” certification.

• As of August 2020, it is still illegal to carry cannabis and cannabis-derived products across the Canadian border.
• The only reason CBDPure scores third place on this list is because of the higher prices.
• CBD’s remarkable anti-inflammatory effects were also demonstrated in vivo in a 2018 study published in the Journal of pharmacology and Experimental Therapeutics.
• Since 2017, FAB CBD has been creating some of the strongest, most innovative CBD products on the market.

Whilst it is clear that this avenue needs to be explored through clinical trials, these findings suggest that CBD may be an effective supplementary therapy for MS. In a long-term trial of Sativex, 92% of participants reported adverse effects over the 2 years — and 25% withdrew from the trial for this reason. But, interestingly, the majority of these side effects can be attributed to the psychoactive properties of THC. Due to the mind-altering effects of THC, it cannot be legally sold in the UK. But CBD— containing negligible amounts of THC— can, and it’s proving to be hugely popular.

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While many studies have suggested CBD oil is helpful for pain, more research is necessary, especially long-term studies with human subjects. However, people may use Epidiolex for children ages 2 and above who have rare forms of epilepsy. In addition, using CBD oil with other medications may make those medications more or less effective. Most people tolerate CBD oil well, but there are some possible side effects.

• I think in milligrams every day; how much is enough, and what amounts can cure you or hurt you.
• In addition, individuals experience pain and respond to treatment in different ways.
• While CBD may offer some benefits over antidepressant medications, it isn’t a replacement.
• New products containing CBD after this deadline will require a fully approved application.
• Verywell Health’s content is for informational and educational purposes only.

Keep in mind that nonprescription CBD products are not FDA-approved, and may be inaccurately labeled. Both CBD and THC are chemically similar to your body’s endocannabinoids. CBD is sold in the form of gels, gummies, oils, supplements, extracts, and more.

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CBD has been federally legal since 2018 when the Farm Bill was passed. This bill made the production, possession, and sale of CBD products legal in the United States. Although over-the-counter products such as CBD oil are not yet FDA approved, you can find them almost anywhere. Although clinical trials are still taking place, CBD has been found to be a great option for people with anxiety. While CBD does come from marijuana plants, it does not create the feeling of being “high”. However, tetrahydrocannabinol , is a constituent that reacts with different receptors in the brain and creates a change of perception.

While CBD may help some people with cancer-related symptoms, research findings are currently mixed, and more research is needed to determine its effectiveness and safety. A review of five studies found some evidence that Sativex may help some people with cancer-related pain . An older study examined the effects of CBD and THC in 177 people suffering from cancer-related pain Bonbons au CBD FAQs who had not found relief from pain medication. Pharmaceutical drugs are frequently used to treat mental health disorders, which can result in drowsiness, agitation, insomnia, sexual dysfunction, and headaches . A study involving 47 people with MS looked at the effects of taking Sativex for a month. The participants’ pain, walking ability, and muscle spasms all improved .

This type of CBD has all of the naturally-occurring chemical compounds in the Cannabis sativa plant. Additionally, patients with CFS are believed to have low red blood cell magnesium. Magnesium treatment is known to help improve the well-being of CFS patients.

• And for the rest of the day, I think about herbal remedies, medical devices, supplements, nutrients, and heavy medication.
• An older study examined the effects of CBD and THC in 177 people suffering from cancer-related pain who had not found relief from pain medication.
• About this, it’s mainly urogynecologists who are beginning to pay attention.
• Despite the many claims regarding the health benefits of CBD oil, not every claim has sufficient evidence to back it up.

At this point, your body’s overall condition has been distorted, and balance needs to be restored. The company offers a variety of CBD strengths – 250, 500, 1,000, and 2,500 milligrams – making it easy for users to find the optimal dosage for their kind of pain. Inthe first study, participants who received 160mg of CBD reported increased sleep duration compared to those who took 5mg of Nitrazepam. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Choose an oral treatment and start with a low dose taken in the evening.

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The most frequent side effects of CBD include symptoms such as a dry mouth, drowsiness, lightheadedness, and drops in blood pressure. If any of these do occur, you should exclude Boutique To You CBD products from therapy. The 2018 Farm Bill made hemp production legal under federal law, which led to an influx of cannabis-derived products into the consumer market.

Many claims are made for the therapeutic benefit of cannabidiol that are not backed by sound evidence. Cannabidiol can be taken internally in multiple ways, including by inhaling cannabis smoke or vapor, by mouth, and as an aerosol spray into the cheek. It may be supplied as CBD oil containing only CBD as the active ingredient (excluding tetrahydrocannabinol or terpenes), CBD-dominant hemp extract oil, capsules, dried cannabis, or prescription liquid solution. CBD does not have the same psychoactivity as THC, and may change the effects of THC on the body if both are present.

• Similar results were observed in a review of similar studies published in The Cochrane Database of Systematic Reviews in 2018.
• People who ordinarily experience debilitating nausea, pain, and other symptoms as a result of their cancer treatment often find that CBD allows them to feel normal again.
• “Earliest evidence for cannabis smoking discovered in ancient tombs”.
• In August 2014, Uruguay legalized growing up to six plants at home, as well as the formation of growing clubs, and a state-controlled marijuana dispensary regime.

“It wasn’t until several friends had remarked that I looked better and they noticed I was able to get out and do more, that I took a step back and began to appreciate the effects of CBD,” he said. For people with this type of MS, symptoms worsen over time with or without flare-ups. The dose of CBD required for symptom relief can vary from person to person, which is why it’s important to work with a practitioner who understands cannabidiol and its uses.

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Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner. In vitro, cannabidiol inhibited the activity of voltage-dependent sodium and potassium channels, which may affect neural activity. A recent study using X-ray crystallography showed that CBD binds inside the sodium channel pore at a novel site at the interface of the fenestrations and the central hydrophobic cavity of the channel.

Hatch suggests you only buy CBD products from a retailer that can provide a document known as a certificate of analysis. This shows the product has been tested in a lab, is free of contaminants, and contains the amount of CBD listed on the label. Cannabidiol acts on the brain’s serotonin receptors and releases feel-good chemicals, helping elevate mood. However, research is underway to investigate how CBD does this, as the exact mechanism of action is not conclusive. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHTAnswers represent the opinions of our medical experts.

• The Farm Bill lifts federal restrictions surrounding CBD and legalizes the cultivation, manufacturing, and sale of these products across the United States.
• These inconsistent findings suggest cannabinoids may provide spasticity relief via other unknown mechanisms.
• Around 2.3 million people worldwide have been diagnosed with multiple sclerosis, a disease that primarily impacts the spinal cord and brain.
• CBD oil is widely available and is usually consumed by placing a few drops under the tongue or stirring into coffee or tea.
• Conditions that destroy or degrade the brain cells, like Alzheimer’s disease, Parkinson’s disease, or stroke, can trigger tremors.
• Although herbal cannabis and industrial hemp derive from the same species and contain the psychoactive component , they are distinct strains with unique biochemical compositions and uses.

It’s best to begin any CBD oil regimen by starting at the lowest dose and then gradually increasing over time. Additionally, while some people think that higher doses are best against pain, the fact of the matter is that mid-range doses work best over higher and lower doses. NuLeaf Naturals’ full-spectrum CBD oils come in 300mg, 600mg, 1200mg, and 3000mg strengths.

If you are considering CBD for a child, consult laws in your state and consider using an isolate that contains no THC, which is illegal for people under 21 even in states that have legalized cannabis. Be sure to purchase your CBD products from a reputable dispensary or drugstore so that you know exactly what’s in them. Verywell Health articles are reviewed by board-certified physicians and healthcare professionals.

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Moreover, psychomotor and psychological functions are not negatively affected. High doses of up to 1,500 mg per day and chronic use have been repeatedly shown to be well tolerated by humans . Cannabidiol has been used by professional and amateur athletes across disciplines and countries, with the World Anti-Doping Agency removing CBD from its banned substances list. The National Hockey League Alumni Association began a project with Canopy Growth to determine if CBD or other cannabis products might improve neurological symptoms and quality of life in head-injured players. Numerous professional athletes use CBD, primarily for treating pain. Approximately 75 to 86% of people with multiple sclerosis experience pain.

• Make sure to check information from reputable academic research institutions, and avoid using tertiary references that may not give the most accurate information.
• High-fat meals can dramatically increase the blood concentrations of CBD, which can increase the risk of side effects.
• In response to subjective survey data, 2 patients were in favor of using cannabis and self-reported relief from their pain conditions.
• Tremors often appear during a stressful event when a person is going through anxiety.

Technically speaking, CBD isolate is the purest form of CBD because it’s pulled directly from hemp plants and does not have other ingredients. On the other hand, full-spectrum CBD contains natural chemicals what is delta thc 8 found in the entire plant, which may include THC. If you are dealing with anxiety signs and symptoms, it’s best to check with your doctor and find a comprehensive, effective treatment plan for you.

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This often happens as a result of inflammation or injury that causes damage to body tissues such as skin, bones, or muscles. However, nerve pain refers to damage caused by an injury to the nerves on their own. He also added that in some cases, it can be damage to one significant nerve or a few minor ones that can contribute to a widespread nerve injury. Dr. Suraj Muley, an esteemed neurologist and director of the neuromuscular division at Barrow Neurological Institute in Phoenix, there are several common points for patients with neuropathy. They usually include electric-like, shooting pain with an ice-cold sensation, sensitivity to touch, and feelings of numbness. These are just a few conditions that can cause nerve damage and lead to neuropathic pain.

• My body felt lighter and within a minute, I fell into a deep sleep.
• However, CBD isn’t the only cannabinoid found in cannabis that can help alleviate neuropathy.
• Cannabidiol is one of many cannabinoids found in the Cannabis sativa plant.
• 2018 study, multiple sclerosis is caused by antigen-specific T cells that trigger neuroinflammation.
• Today, more people are learning about the healing power of CBD as they research natural alternative methods to help calm and eventually end their pain.

For students with generalized social anxiety, a four-minute talk, with minimal time to prepare, can be debilitating. Yet a small experiment in the journal Neuropsychopharmacology found that CBD seemed to reduce nervousness and cognitive impairment in patients with social anxiety in a simulated public speaking task. Cannabidiol and THC are just two of the plant’s more than 100 cannabinoids.

Lauren Silva, a freelance writer in New York City, believes in feeling good in your body and making that experience accessible to everyone across generations. The proof is in her ever-piling browser tabs and newsletters, which help her stay on top of the latest wellness trends. When she’s not researching sustainable alternatives to her everyday products, Lauren is likely attempting to make a dent in her “TBR” book pile. Researchers found can cbd oil help ed that, compared to a placebo, Sativex significantly improved participants’ pain during movement, pain at rest and quality of sleep. Any adverse reactions to the treatment were mild or moderate, and there were no complications with withdrawal. Interestingly, 60% of U.S. adults who use CBD products do so for its potential pain-relieving effects, according to a recent Forbes Health survey of 2,000 U.S. adults conducted by OnePoll.

Capsules and edibles are a great option if you want to ease nerve pain in social settings, or when you need longer-lasting relief at the cost of delayed onset. According to the American Chronic Pain Association, neuropathic pain is the type of chronic pain that occurs in the nerves in the peripheral nervous system due to injury or damage. Some forms of neuropathy can be easily treated and sometimes cured. If neuropathy is incurable, the treatment should aim at preventing further damage to the nerve and controlling symptoms. The nerves are important players for any kind of pain, as well as other types of sensations. According to Dr. Ryan Jacobs, a neuromuscular neurologist, pain messages are sent by the nerves.

The idea is to get a pure product that contains the right amount of CBD and not any other harmful chemicals if you really want to tap into the benefits of this natural treatment. In other words, CBD potentially has what it takes to give MS patients the chance to enjoy a more comfortable life by carrying out their daily activities as they please and sleeping better at night. Furthermore, overdosing with CBD is almost impossible to achieve, and the risks of side effects are almost nonexistent. The purpose Sind Gummibärchen-Dosen mit 3000mg CBD auch für Anfänger geeignet? of this study was to determine if pure CBD can counteract the development of experimental multiple sclerosis. Cannabinoids have been found to activate so-called pathways across multiple immune and non-immune cells, however, it is not yet known what impact CBD has on these pathways in treating MS. The so-called adenosine A2A receptors participate in some of the anti-inflammatory effects of CBD since the A2A antagonist partially blocks the protective effects of CBD in the initial stages of inflammation.

Or from scraping the resin from the surface of the plants and rolling it into balls. It varies in color from black to golden brown depending upon purity and variety of cultivar it was obtained from. It can be consumed orally or smoked, and is also vaporized, or ‘vaped’. The term “rosin hash” refers to a high quality solventless product obtained through heat and pressure. Hemp buds (or low-potency cannabis buds) laced with synthetic cannabinoids started to be sold as cannabis street drug in 2020. Australia’s National Cannabis Prevention and Information Centre states that the buds of the female cannabis plant contain the highest concentration of THC, followed by the leaves.

Research-grade samples of the drug are difficult to obtain for research purposes, unless granted under authority of national regulatory agencies, such as the US Food and Drug Administration. In 1997, cannabis was estimated to be overall the number four value crop in the US, and number one or two in many states, including California, New York, and Florida. This estimate is based on a value to growers of ~60% of retail value, or $3,000 per pound ($6,600/kg). The average levels of THC in cannabis sold in the United States rose dramatically between the 1970s and 2000. This is disputed for various reasons, and there is little consensus as to whether this is a fact or an artifact of poor testing methodologies. According to Daniel Forbes writing for slate.com, the relative strength of modern strains are likely skewed because undue weight is given to much more expensive and potent, but less prevalent, samples.

Other findings indicate that hard drug users are likely to be poly-drug users, and that interventions must address the use of multiple drugs instead of a single hard drug. Almost two-thirds of the poly drug users in the 2009–2010 Scottish Crime and Justice Survey used cannabis. Sinsemilla (Spanish for “without seed”) is the dried, seedless (i.e. parthenocarpic) infructescences of female cannabis plants.

• In vitro, cannabidiol inhibited the activity of voltage-dependent sodium and potassium channels, which may affect neural activity.
• CB1 receptors are involved in-memory processing, pain sensation, mood, sleep, and motor regulation.
• When conventional treatments do not work to control seizures, as is the case for roughly 30% of people with epilepsy, it is not unreasonable to consider CBD oil.
• However, research on the effects of cannabis and cannabinoids like CBD on cancer-related nausea, pain, and decreased appetite has yielded conflicting results .

Today, more people are learning about the healing power of CBD as they research natural alternative methods to help calm and eventually end their pain. To date, there are a wealth of studies that support evidence of CBD’s pain-relieving benefits. It’s also encouraging that these studies are also backed up by verified customer reviews and published articles written by both can cbd oil help with insomnia CBD journalists and experts in the cannabis field. As the legal use of hemp and other cannabis products grows, consumers are becoming more curious about their options. This includes cannabidiol and tetrahydrocannabinol , two natural compounds found in plants of the Cannabis genus. Innovet created a product line of full-spectrum, pure hemp oils void of dangerous compounds.

A physician may check for such things as sensory loss using a pinprick on different parts of the body. If the patient doesn’t feel the impulse from the pinprick or other things, that could indicate neuropathy, as said by Dr. Eva Feldman, a professor of neurology at the University of Michigan. Speaking of high-potency oils, the 2500 mg bottle is my favorite product from Royal CBD. The hemp aftertaste is surprisingly mild because the oil has been infused into food-grade coconut-derived MCT oil. This adds another benefit because MCT oil also enhances the absorption of CBD. While the FDA recognizes the potential benefits that CBD provides, it’s still implementing ways to regulate the substance in order to protect the safety and health of all consumers. Unlike THC, CBD simply creates therapeutic effects such as relaxation or pain relief, instead of any psychoactive effects that alter your mental state.

Also, keep in mind that non-prescription CBD products are not FDA-approved and may be labelled incorrectly. Most typically in the form of capsules or gummies, oral CBD gives you a consistent and convenient dose and, unlike CBD oil, there is no strong taste! CBD pills typically contain lower doses and take up to 2 hours to kick in; but, when taken daily, CBD accumulates in your system over time, allowing its beneficial effects to gradually build.

• Certain state regulations are in place, but vary state to state.
• Founded in 1884, the not-for-profit AKC is the recognized and trusted expert in breed, health, and training information for all dogs.
• Any psychoactive cannabis, regardless of its CBD content, is derived from the flower of the genus Cannabis.
• In addition to the fact that they are risk-free, natural, and effective, they do not also require any prescription.

Smoking cannabis has also been shown to increase the risk of myocardial infarction by 4.8 times for the 60 minutes after consumption. While cannabis plants have been grown since at least the 3rd millennium BCE, evidence suggests that it was being smoked for psychoactive effects at least 2,500 years ago in the Pamir Mountains. Since the early 20th century, cannabis has been subject to legal restrictions. The possession, use, and cultivation of cannabis is illegal in most countries. In 2013, Uruguay became the first country to legalize recreational use of cannabis.

Anyone struggling with insomnia is likely to sleep at least a bit better when using broad-spectrum CBD. Most adults can benefit from the use of CBD products in some way. However, some people have a greater need for its benefits than others. Less processing – CBD isolate, the other THC-free option, has to be heavily processed in order to remove all other compounds. Broad-spectrum CBD still has almost everything else in it, so it is much closer to the natural state of the cannabinoids than isolate is. Lastly, you should consult with your primary care doctor or prescribing physician before adding anything new to your daily holistic supplement regimen.

However, 33 states plus Washington, D.C., have passed cannabis-related laws, making medical cannabis with high levels of THC legal. CBD needs THC to bind to the CB1 receptor and, in turn, can help reduce some of the unwanted psychoactive effects of THC, such as euphoria or sedation. THC is the main psychoactive compound in cannabis that produces the high sensation. It’s also available in oils, edibles, tinctures, capsules, and more. It seems to help with both the inflammation that can lead to breakouts and the amount of fatty acids in the blood, which can make them worse. Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.

There is empirical evidence that marijuana can help with lupus symptoms, such as nervousness, pain, indigestion, seizures, and eye problems. However, there are higher chances of psychoactive side effects with the use of THC preparations. CBD helps reduce the hyperactivity of the immune system that is responsible for autoimmune disease development. There is clinical evidence that supports the benefits of CBD in treatments of rheumatoid arthritis and fibromyalgia, which are considered autoimmune diseases. There is no evidence that CBD products can worsen lupus symptoms or onset lupus flare-ups. They are considered helpful but not officially prescribed by doctors.